Pneumococcal Pneumonia Innate Immune Responses during Type I Alveolar Epithelial Cells Mount
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Alveolar Epithelial Cells, and Mouse Lungs Production in Macrophages, Cocultured Macrophages, which Regulates RANTES 3-Dependent Type I IFN Production in STING- and IFN Regulatory Factor Stimulates a Streptococcus pneumoniae
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia. In this study, we examine an innate immune recognition pathway that senses pneumococcal infection, triggers type I IFN production, and regulates RANTES production. We found that human and murine alveolar macrophages as well as murine bone marrow macrophages, but not alveolar epithelial cells, produced type I IFNs upo...
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تاریخ انتشار 2012